Centralised Facility for Bioassay
The Centralised Facility for Bioassays (CFB) was set up in May 2018 (vide office order no. 30/2018-19 dated 17.05.2018) at Ground floor (L0048) of Laboratory Block with two biosafety modules to cater the cell based bioassays as a part of quality control evaluation for various recombinant products like peg-Erythropoietin, Filgratism, Interferon, Therapeutic Antibodies, Immunoglobulin etc. and other therapeutic proteins referred by various product testing laboratories at NIB. Recently, the CFB has been shifted to upgraded facility at 2nd floor (L2028) of Laboratory Block with four biosafety modules and declared open by Director Incharge, NIB on 08th June, 2020.
The CFB is equipped with workstations Class II type B2 Biosafety cabinets, Centrifuges, CO2 incubators, Refrigerators/Freezers, Microscopes, Cell counters, Cryopreservation equipment and Multi-mode plate reader for detection mode of absorbance, luminescence, fluorescence, and time-resolved fluorescence (TRF) for cell-based immunogenicity assays and bioassays including Anti-Proliferation assays, Complement dependent cytotoxicity (CDC), Antibody dependent cell mediated cytotoxicity (ADCC), Apoptosis assays, Reporter gene assays, Neutralization assays.